%0 Journal Article
%A BAI Chen
%A HU Shu-Min
%A SHI Ya-Nan
%A XU Hao-Peng
%A YIN Hua
%A YIN Lian
%A ZHAO Shan-Bo
%A ZHU Hong-Wei
%A ZHANG Xiao-Nan
%T Optimization of Ultrasound-assisted Extraction of Dihydromyricetin from Seeds of <i>Hovenia dulcis</i> Thunb. Using Response Surface Methodology
%D 2020
%R 10.7525/j.issn.1673-5102.2020.05.017
%J Bulletin of Botanical Research
%P 775-781
%V 40
%N 5
%X Dihydromyricetin is an important component in the seeds of <i>Hovenia dulcis</i> Thunb. The extraction of dihydromyricetin from seeds of <i>H.dulcis</i> by ultrasound-assisted method was carried out on the basis of single factor investigation of ethanol volume fraction, ultrasound irradiation power, extraction temperature, liquid-solid ratio and ultrasound irradiation time. The Box-Behnken response surface design method was used to establish a quadratic polynomial model of ultrasound irradiation power, ultrasound irradiation time and liquid-solid ratio, and optimized extraction process. The optimum conditions for the extraction were as follows:ethanol volume fraction of 60%, ultrasonic irradiation power of 140 W, ultrasonic irradiation time of 30 min, liquid-solid ratio of 20.5 mL&#183;g<sup>-1</sup>, and extraction temperature of 40℃. Under these optimal conditions, the yield of dihydromyricetin was 2.14&#177;0.09 mg&#183;g<sup>-1</sup>. The extraction method is simple, rapid, and high in efficiency, which is beneficial to the comprehensive processing and utilization of the <i>H.dulcis</i> resources.
%U https://bbr.nefu.edu.cn/EN/10.7525/j.issn.1673-5102.2020.05.017