%0 Journal Article
%A GAO Li-Hong
%A HAN Guo-Jun
%A NI Xiu-Zhen
%A SHENG Yan-Min
%A YU Ting-Ting
%A ZHU Chang-Fu
%T Advances in Study of Dihydroflavonol 4-Reductase(DFR) Genes of Higher Plants
%D 2018
%R 10.7525/j.issn.1673-5102.2018.04.020
%J Bulletin of Botanical Research
%P 632-640
%V 38
%N 4
%X Anthocyanins are important pigments for flower color of higher plants which is an important factor determining the appreciation value and economic value of floriculture plants. Dihydroflavonol 4-reductase(DFR) is a key enzyme involved in the late steps of the anthocyanin biosynthetic pathways. Thus, DFR is an important regulatory point for the formation of anthocyanins, which plays an important role in the formation of flower color. DFRs have different substrate specificities for three dihydroflavonols(dihydrokaempferol, dihydromyricetin and dihydroquercetin); however, the mechanism of substrate specificity determination in DFRs is still unclear. This paper summarizes the anthocyanin biosynthetic pathway and its transcriptional regulation mechanism. Combined with the authors' work, the substrate specificity of the dihydroflavonol 4-reductase(DFR) and the application of the cloned DFR gene in plant genetic engineering were extensively reviewed.
%U https://bbr.nefu.edu.cn/EN/10.7525/j.issn.1673-5102.2018.04.020