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Bulletin of Botanical Research ›› 2024, Vol. 44 ›› Issue (6): 805-811.doi: 10.7525/j.issn.1673-5102.2024.06.001

• Review •     Next Articles

Research Progress of Plant Growth, Development and Stress Resistance Traits Regulated by Liquid-liquid Phase Separation-mediated Gene Expression

Qingqing XU, Dehui SUN, Wenmeng WANG, Dangdang LI, Xingguo LAN, Guangchao SUI()   

  1. College of Life Sciences,Northeast Forestry University,Harbin 150040
  • Received:2024-05-14 Online:2024-11-20 Published:2024-11-22
  • Contact: Guangchao SUI E-mail:gcsui@nefu.edu

Abstract:

Gene expression determines the growth, differentiation, and various traits and functions of multicellular organisms. In this process, transcriptional regulation is one of the most critical steps of gene expression. Since 2018, gene expressions regulated by the liquid-liquid phase-separated condensates formed by biological macromolecules in mammalian cells have been continuously revealed. However, the research in understanding the role of phase separation in the gene transcription process of plant cells has achieved relatively limited progression. In this review, we first introduced the mechanisms of phase separation-regulated gene expression, discussed its relevant basic research approaches, and summarized key findings in the mechanistic studies of phase separation in regulating gene transcription during the growth, development and stress response of plants. Finally, we provided our perspectives for future researches to expand and deepen the understanding of phase separation regulation mechanisms of plant gene expression.

Key words: liquid-liquid phase separation, biological macromolecules, plant cells, gene expression, transcriptional regulation

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